BANF1 anticorps (Middle Region)
Aperçu rapide pour BANF1 anticorps (Middle Region) (ABIN2789779)
Antigène
Voir toutes BANF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- FDKAYVVLGQ FLVLKKDEDL FREWLKDTCG ANAKQSRDCF GCLREWCDAF
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%
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Attributs du produit
- This is a rabbit polyclonal antibody against BANF1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human BANF1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 89 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BANF1 (Barrier To Autointegration Factor 1 (BANF1))
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Autre désignation
- BANF1
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Sujet
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The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.
Alias Symbols: BAF, BCRP1, D14S1460, MGC111161
Protein Interaction Partner: UBC, ERBB2IP, HIST1H3B, EMD, FBL, CRX, ATP6V1B1, LUC7L3, TMPO, EHMT2, SET, EVC2, ZNF428, LMNB2, DPY30, SMOC2, APTX, ACIN1, CBX3, PSIP1, CBX1, SUB1, CD2BP2, MDC1, BCL7C, MTA2, BANF1, CUL4A, CHAF1B, XPC, TUFM, SNRPD3, SMARCE1, SMARCC2, SMARCA2, TRA2B, DPF2,
Protein Size: 89 -
Poids moléculaire
- 10 kDa
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ID gène
- 8815
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NCBI Accession
- NM_003860, NP_003851
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UniProt
- O75531
Antigène
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